I-one Bone Growth Stimulator Efficacy and safety for the patient

I-ONE therapy is a local treatment that can permeate joints evenly and articular cartilage in all its extent and thickness; effectively controls inflammation and protects cartilage, while maintaining the mechanical competence.

I-ONE therapy was developed within the "C.R.E.S. study" (Cartilage Repair and Electromagnetic Stimulation), which has demonstrated the chondroprotective efficacy of the treatment. I-ONE therapy is indicated after joint surgery and in early stages of osteoarthritis.

I-ONE therapy shortens patients' full recovery. I-ONE therapy clears up the patient from pain and joint swelling quickly.

I-ONE is a highly reliable device, manufactured to meet the most rigorous European safety standards. It is built in compliance with the IEC 601-1 standard, its electrical safety is IMQ tested, and it meets the requirements of directive 93/42/EEC. It is CE0051 marked.

I-ONE therapy

Three therapeutic actions with IGEA technology

• Anti-inflammatory action:
  I-ONE therapy acts as agonist specifically on the A2A adenosine receptors on the cell membrane, and inhibits the negative effect of the pro-inflammatory cytokines.
• Anabolic action on cartilage:
  I-ONE therapy promotes the synthesis of proteoglycans by the chondrocytes.
• Action on the subchondral bone:
  I-ONE therapy promotes the activation of the osteogenetic processes of the subchondral bone.

Brochure
Technical Information

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