ReproBone novo™ Nanocrystalline Synthetic Bone Graft Paste

ReproBone novo™ has proven biocompatibility and bone regenerative properties. Studies show that ReproBone novo™ implanted in cancellous bone provides excellent osseointegration with rapid vascularisation and bone penetration through to the core of the implant.

APPLICATION & PRIMARY STAGES
The non-hardening mouldable paste does not form a barrier to adjacent healthy bone cells, the sticky paste ensures good contact and cells readily migrate inwards. Blood passively infiltrates, bringing with it the growth factors needed for bone regeneration, and early vascularisation takes place.

BONE FORMATION
ReproBone novo™ stimulates bone healing by accelerating the rate at which bone-forming cells proliferate, resulting in a rapid building of new bone.

The bone defect is regenerated with new woven bone after several weeks. In parallel the graft has been almost completely resorbed by macrophages and osteoclasts. Remodelling and maturation of the bone continues as normal.

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